What to expect from treatment with
Tri-Luma® Cream

Tri-Luma® Cream (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) may improve your melasma, but it is not a cure.

In studies, after 8 weeks of treatment with Tri-Luma® Cream, most patients with moderate-to-severe melasma had at least some improvement. Some had their dark spots clear up completely (38% in one study and 13% in another). In most patients treated with Tri-Luma® Cream, their melasma came back after treatment was discontinued.

If the underlying causes of melasma—such as the use of certain birth control pills or too much exposure to sunlight—are not removed, melasma will come back when you stop treatment.